Metronidazole – What It Is, How to Take It, and What to Watch For
If a doctor has prescribed metronidazole, you probably have a bacterial or parasite infection they want to knock out. It’s an antibiotic that’s been around for decades, so you can trust it works when used correctly. This guide breaks down the basics: why it helps, how to dose it, and the most common things to keep an eye on.
How Metronidazole Works
Metronidazole attacks anaerobic bacteria – the kinds that thrive without oxygen – and certain parasites like Giardia. It gets inside the microbe, damages its DNA, and stops it from reproducing. That’s why it’s a go‑to drug for gum infections, bacterial vaginosis, certain gut bugs, and some skin conditions.
Because it targets specific germs, it usually doesn’t affect the good bacteria in your gut as much as broad‑spectrum antibiotics. Still, you might feel a little upset stomach, which is normal and often fades after a few days.
Key Safety Tips and Common Side Effects
Take metronidazole exactly as your doctor says. The usual adult dose is 500 mg every 8 hours for 7‑10 days, but the amount can change based on the infection. Swallow the tablets with food or a full glass of water to avoid stomach irritation.
Alcohol is a big no‑no while you’re on metronidazole and for at least 24 hours after the last dose. Mixing the two can cause a nasty reaction: flushing, rapid heartbeat, nausea, and headache. If you enjoy a glass of wine, plan to skip it until the medication is fully cleared from your system.
Typical side effects include a metallic taste, mild nausea, and occasional headache. Most people get through the course without trouble. If you notice severe dizziness, dark urine, a rash, or signs of an allergic reaction, call your doctor right away.
Metronidazole can interact with several other medicines, especially blood thinners like warfarin and certain anti‑seizure drugs. Let your pharmacist know every medication you’re taking, including over‑the‑counter supplements.
Pregnant or breastfeeding women should only use metronidazole if the doctor says it’s absolutely needed. The drug crosses the placenta, but studies show low risk when used in the second or third trimester. Still, always double‑check with your healthcare provider.
Storing metronidazole is simple: keep it at room temperature, away from moisture and direct sunlight. Throw away any tablets that are past their expiration date – they may lose potency.
Bottom line: metronidazole is a reliable, targeted antibiotic when you follow the dosage instructions, avoid alcohol, and watch for side effects. If you have any doubts during treatment, your doctor or pharmacist can help you stay safe and get better fast.

Antibiotics for Bacterial Vaginosis: Benefits, Risks, and What to Expect
Explore how antibiotics treat bacterial vaginosis, their pros and cons, side‑effects, resistance issues, and alternative approaches to help you decide the best course.
More Detail