Ketorolac – What You Need to Know About This Fast‑Acting Painkiller
Ketorolac is a short‑term pain reliever that belongs to the NSAID family (non‑steroidal anti‑inflammatory drug). It’s known for kicking in quickly, which makes it a popular choice after surgeries, dental work, or severe injuries. Unlike some opioids, ketorolac doesn’t cause a high, but it does pack a potent anti‑pain punch.
Because it reduces inflammation as well as pain, ketorolac can help with swelling, fever, and the aches that come with tissue damage. It works by blocking enzymes called COX‑1 and COX‑2, which are needed for the body to produce prostaglandins – the chemicals that cause pain and inflammation.
How to Use Ketorolac Safely
Ketorolac is usually prescribed for no more than five days. The drug comes in oral tablets, injectable form, and an eye drop version for eye surgery. If you get a tablet, the typical adult dose is 10 mg every 4‑6 hours, not exceeding 40 mg in a day. For injections, doctors often start with a 30 mg dose and may repeat it after 6‑8 hours if needed, but they keep the total under 120 mg in 24 hours.
Take ketorolac with food or milk to reduce stomach irritation. Avoid alcohol while you’re on it because both can increase the risk of bleeding. If you have a history of ulcers, kidney problems, or heart disease, tell your doctor – they might choose a different painkiller.
Never use ketorolac longer than prescribed. Even if the pain subsides, extending the course can lead to serious side effects. Keep track of how many pills you’ve taken and set a reminder to stop after the recommended period.
Potential Risks and When to Seek Help
The most common side effects are stomach upset, nausea, and headache. Some people notice bruising or mild bleeding gums. If you see black or bloody stools, vomit blood, or develop a sudden severe stomach pain, stop the medication and call a doctor right away – these could be signs of a bleeding ulcer.
Kidney function can drop quickly with ketorolac, especially in older adults or those who are dehydrated. Make sure to stay hydrated, but avoid excess fluids if you have heart failure. If you notice reduced urine output, swelling in ankles, or shortness of breath, get medical help.
Ketorolac can interact with other drugs like blood thinners (warfarin, aspirin), other NSAIDs, certain antidepressants, and high‑dose diuretics. Always give your pharmacist a full list of medicines you’re taking.
Pregnant women should steer clear of ketorolac, especially in the third trimester, because it can affect the newborn’s heart and circulation. Breastfeeding mothers should also avoid it unless a doctor says it’s safe.
In short, ketorolac is a powerful tool for short‑term pain, but it demands careful use. Stick to the prescribed dose, watch for warning signs, and keep an open line with your healthcare provider. When used correctly, you’ll get fast relief without the long‑term risks that come with some other pain meds.

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